The clinical and economic importance Amoeba in medicine and human health

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Amoeba falls into the class of protozoa Lobezea strain. The Lobezea organisms, which move using pseudopodiás. Reproduction binary fission. The production of one of the cyst stage of the life cycle. Among the pathogenic species of human Entamoeba histolytica. A pathogen against human intestinal amoebic or amoebic dysentery.

Morphology

Enteroamoeba histolyca occurs in the human body as a form of

1. Entamoeba histolytica form magna form of a vegetative large tissue that nourishes the red blood cells, and it becomes encysted

2. Entamoeba histolytica minuta form a commensal encysted small vegetative form that live in the lumen of the colon.

3. cysts, which develop in the same minuta. E.histolytica penetrates the target tissue during colon many factors effect (decreased resistance, due to the human body from various diseases, poisoning, overheating, overstrian, injuries, substances that cause lysis of cells and tissues. The parasite growing size from 30 to 50 micrometers in diameter and becomes able phagocytizing erythrocytes. This vegetative form known as form the fabric. Entamoeba histolytica shape magna. It is usually found on the mucous stool (feces blood or mucus) in the patient Amebiasis. amoeba ectoplasm translucent while endoplasm granulated. the endoplasm includes the nucleus and food vacoules. the core is the main form a central karyosome. form minuta E.histolitica. the size range of 12-25 microns. bacteria in phagocytes can be found in small numbers in endoplasm. ectoplasm poorly developed and accumulated at his feet, motility is reduced. Amoebas live in the upper part of the colon in healthy male and luminal known, commensal or cavity forms. the forms minuta turns into a cyst. The cysts are in spherical shape with a diameter of 9-16 micrometers. These thin walled, double membrane, fully mature cysts containing four seeds. Immature cysts have one, two and sometimes three cores. Cysts are discharged in the feces for a long time, and sometimes throughout life. May re-enter the human body and foods or water, and transform into the lumen formed in the intestine.

and the pathogenesis of disease

faecal-oral transmission cysts include contaminated food or water, ingested cysts E.histolytica excysts the small intestine. Trophozoites (minuta form) is made to the colon, where mature and reproduce. Form minuta can live in the lumen as a commensal. Successful colonization and transforming same into minuta Magna form depends on factors such as intestinal motility and transit time, the presence or absence of specific intestinal flora of the host diet. If mucosal invasion occurs, it may take a few simple superficial erosion or may progress to involve the entire colon mucosal ulceration, most commonly in the sigmoid and cecum. Patients with acute or chronic diarrhea, which can undergo Hemorragic dysentery. Invasion of the blood vessels leads to a secondary extra intestinal lesions. Extraintestinal disease may be present as a complication (peritonitis) or metastasis (liver, lung, skin and brain abscess.)

Laboratory Diagnostics

Fresh feces were examined under a microscope. E.histolytica (magna form cysts and 4 nuclei) can be detected in the faeces.

Prophylaxis

All patients were transferred to the hospital and treated appropriately. protection of food and water be amoebic preventive measures against dirt and feces. The staff should be examined cysts car hospitality applications. Health education of the population.

Non-pathogenic amoebae is a parasite of the human gastrointestinal tract. These include Entamoeba gingivalis (mouth), Entamoeba coli (large intestine) and the E. coli is greater than E.histolytica. Granular cytoplasm and vacuoles containing bacteria, white blood cells, food particles, and glycogen, but not red blood cells. E. Coli forms cysts eight cores, E.gingivalis not form cysts.

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Source by Funom Makama

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